On Sunday morning, Alexis' brother Richmond Arquette reportedly confirmed the news on his Facebook page writing, "Our brother Robert, who became our brother Alexis, who became our sister Alexis, passed this morning September 11 at 12:32 a.m. He was surrounded by all of his brothers and sisters, and one of his nieces and several other loved ones. We were playing music for him and he passed during David Bowie's Starman. As per his wishes, we cheered at the moment that he transitioned to another dimension."
Sister Patricia Arquette later tweeted, "To My first best friend - Cosmic Dancer. Breaking through the veil singing StarMan."
Fans may remember Alexis from her roles in Last Exit to Brooklyn, Pulp Fiction and as a Boy George impersonator in The Wedding Singer. She also starred in Vh1's reality show titled The Surreal Life.
Our thoughts and prayers go out to her family during this difficult time.